"There's a war being waged - a top-secret and high-tech war that humans are blissfully unaware of! It's the eternal war between the two great armies of Cats and Dogs! The plot of the Cat army to destroy a new vaccine that, if developed, would destroy all human allergies to Dogs, is uncovered and the Dogs fight back to prevent the Cats from succeeding in their quest for domination! Includes cutting-edge CGI and animatronic special effects, with the voice talents of Emmy and Golden Globe nominee Alec Baldwin (""Pearl Harbor"", ""Nuremberg""), Academy and Golden Globe nominee Michael Clarke Duncan (""See Spot Run"", ""The Green Mile"") and Joe Pantoliano (""The Sopranos"", ""The Matrix"")."
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